Research papers

2022

• Asadishekari, M., Mpoyi, E. N., Li, Y., Eslami, J., Walker, M. , Cantini, M. and Gourdon, D. (2022) Three-dimensional tunable fibronectin-collagen platforms for control of cell adhesion and matrix deposition. Frontiers in Physics, 10, 806554. (doi: 10.3389/fphy.2022.806554)
• Xiao, Y., Donnelly, H., Sprott, M. , Luo, J., Jayawarna, V., Lemgruber, L. , Tsimbouri, P. M. , Meek, R.M. D., Salmeron-Sanchez, M. and Dalby, M. J. (2022) Material-driven fibronectin and vitronectin assembly enhances BMP-2 presentation and osteogenesis. Materials Today Bio, 16, 100367. (doi: 10.1016/j.mtbio.2022.100367)
• Luo, J., Walker, M. , Xiao, Y., Donnelly, H., Dalby, M. J. and Salmeron-Sanchez, M. (2022) The influence of nanotopography on cell behaviour through interactions with the extracellular matrix – a review. Bioactive Materials, 15, pp. 145-159. (doi: 10.1016/j.bioactmat.2021.11.024)
• Petaroudi, M., Rodrigo-Navarro, A. , Dobre, O. , Dalby, M. J. and Salmeron-Sanchez, M. (2022) Living biomaterials to engineer haematopoietic stem cell niches. Advanced Healthcare  Materials, (doi: 10.1002/adhm.202200964) (PMID:35933595) (Early Online Publication)
• Xiao, Y., McGuinness, C. A.S., Doherty-Boyd, W. S., Salmeron-Sanchez, M. , Donnelly, H. and Dalby, M. J. (2022) Current insights into the bone marrow niche: from biology in vivo to bioengineering ex vivo. Biomaterials, 286, 121568. (doi: 10.1016/j.biomaterials.2022.121568) (PMID:35580474)
• Anderson, H. J., Sahoo, J. K., Wells, J., van Nuffel, S., Dhowre, H. S., Oreffo, R. O.C., Zelzer, M., Ulijn, R. V. and Dalby, M. J. (2022) Cell-controlled dynamic surfaces for skeletal stem cell growth and differentiation. Scientific Reports, 12, 8165. (doi: 10.1038/s41598-022-12057-z) (PMID:35581256) (PMCID:PMC9114122)
• Dhawan, U., Jaffery, H., Salmeron-Sanchez, M. and Dalby, M. J. (2022) An ossifying landscape: materials and growth factor strategies for osteogenic signalling and bone regeneration. Current Opinion in Biotechnology, 73, pp. 355-363. (doi: 10.1016/j.copbio.2021.10.010) (PMID:34735985)
• Damiati, L. A. et al. (2022) Materials-driven fibronectin assembly on nanoscale topography enhances mesenchymal stem cell adhesion, protecting cells from bacterial virulence factors and preventing biofilm formation. Biomaterials, 280, 121263. (doi: 10.1016/j.biomaterials.2021.121263) (PMID:34810036)
• Luo, J. et al. (2022) TiO2 nanotopography-driven osteoblast adhesion through Coulomb’s force evolution. ACS Applied Materials and Interfaces, 14(30), pp. 34400-34414. (doi: 10.1021/acsami.2c07652) (PMID:35867934)
• Ciccone, G., Azevedo Gonzalez Oliva, M., Antonovaite, N., Lüchtefeld, I., Salmeron-Sanchez, M. and Vassalli, M. (2022) Experimental and data analysis workflow for soft matter nanoindentation. Journal of Visualized Experiments, 179, e63401. (doi: 10.3791/63401)

2021

• Schofield, C. L., Rodrigo-Navarro, A. , Dalby, M. J. , Van Agtmael, T. and Salmeron-Sanchez, M. (2021) Biochemical­­– and biophysical–induced barriergenesis in the blood brain barrier: a review of barriergenic factors for use in in vitro models. Advanced NanoBiomed Research, 1(5), 2000068. (doi: 10.1002/anbr.202000068)
• Barcelona Estaje, E., Dalby, M. J. , Cantini, M. and Salmeron-Sanchez, M. (2021) You talking to me? Cadherin and integrin crosstalk in biomaterials design. Advanced Healthcare Materials, 10(6), 2002048. (doi: 10.1002/adhm.202002048) (PMID:33586353)
• Dobre, O. et al. (2021) A hydrogel platform that incorporates laminin isoforms for efficient presentation of growth factors – neural growth and osteogenesis. Advanced Functional Materials, 31(21), 2010225. (doi: 10.1002/adfm.202010225)
• Rodrigo-Navarro, A. , Sankaran, S., Dalby, M. J. , del Campo, A. and Salmeron-Sanchez, M. (2021) Engineered living biomaterials. Nature Reviews Materials, 6(12), pp. 1175-1190. (doi: 10.1038/s41578-021-00350-8)
• Kennedy, J.D., Tsimbouri, M.P., Campsie, P., Sood, S., Childs, P.C., Reid, S., Young, P.S., Meek, D.R.M., Goodyear, C.S., Dalby, M.J. (2021) Nanovibrational stimulation inhibits osteoclastogenesis and enhances osteogenesis in co‑cultures. Scientific Reports, 11:22741 (DOI: 10.1038/s41598-021-02139-9) (PMID: 34815449)
• Dhawan, U., Jaffery, H., Salmeron-Sanchez, M. and Dalby, M.J. (2021) An ossifying landscape: materials and growth factor strategies for osteogenic signaling and bone regeneration. Current Opinion in Biotechnology, 73, pp. 355-363. (doi: 10.1016/j.copbio.2021.10.010)
• Ciccone, G., Azevedo Gonzalez Oliva, M., Antonovaite, N., Lüchtefeld, I., Salmeron-Sanchez, M. and Vassalli, M. (2021) Experimental and data analysis workflow for soft matter nanoindentation. Journal of Visualized Experiments, (Accepted for Publication)
• Damiati, L.A., Tsimbouri, M.P., Llopis-Hernandez, V., Jayawarna, V., Ginty, M., Childs, P., Xiao, Y., Burgess, K., Wells, J., Sprott, M.R., Meek, R.M.D., Li, P., Oreffo, R.O.C., Nobbs, A., Ramage, G., Su, B., Salmeron-Sanchez, M. and Dalby, M.J. (2021) Materials-driven fibronectin assembly on nanoscale topography enhances mesenchymal stem cell adhesion, protecting cells from bacterial virulence factors and preventing biofilm formation.Biomaterials, (doi: https://doi.org/10.1016/j.biomaterials.2021.121263) (Accepted for Publication)
• Gavazzo, P., Viti, F., Donnelly, H., Oliva, M. A. G., Salmeron-Sanchez, M. , Dalby, M. J. and Vassalli, M. (2021) Biophysical phenotyping of mesenchymal stem cells along the osteogenic differentiation pathway. Cell Biology and Toxicology, (doi: 10.1007/s10565-020-09569-7) (PMID:33420657) (Early Online Publication)
• Schofield, C. L., Rodrigo-Navarro, A. , Dalby, M. J. , Van Agtmael, T. and Salmeron-Sanchez, M. (2021) Biochemical­­– and biophysical–induced barriergenesis in the blood brain barrier: a review of barriergenic factors for use in in vitro models. Advanced NanoBiomed Research, 1(5), 2000068. (doi: 10.1002/anbr.202000068)
• Barcelona Estaje, E., Dalby, M. J. , Cantini, M. and Salmeron-Sanchez, M. (2021) You talking to me? Cadherin and integrin crosstalk in biomaterials design. Advanced Healthcare Materials, 10(6), 2002048. (doi: 10.1002/adhm.202002048) (PMID:33586353)
• Morales, J. M., Hammarström, B., Lippi, G. L., Vassalli, M. and Glynne-Jones, P. (2021) Acoustofluidic phase microscopy in a tilted segmentation-free configuration. Biomicrofluidics, 15(1), 014102. (doi: 10.1063/5.0036585)
• Sarrigiannidis, S. O., Rey, J. M., Dobre, O. , Gonzalez Garcia, C., Dalby, M. J. and Salmeron-Sanchez, M. (2021) A tough act to follow: collagen hydrogel modifications to improve mechanical and growth factor loading capabilities. Materials Today Bio, 10, 100098. (doi: 10.1016/j.mtbio.2021.100098) (PMID:33763641) (PMCID:PMC7973388)
• Hodgkinson, T. et al. (2021) The use of nanovibration to discover specific and potent bioactive metabolites that stimulate osteogenic differentiation in mesenchymal stem cells. Science Advances, 7(9), eabb7921. (doi: 10.1126/sciadv.abb7921) (PMID:33637520)
• Dobre, O. et al. (2021) A hydrogel platform that incorporates laminin isoforms for efficient presentation of growth factors – neural growth and osteogenesis. Advanced Functional Materials, 31(21), 2010225. (doi: 10.1002/adfm.202010225)

2020

• Papalazarou, V., Zhang, T., Paul, N. R., Juin, A., Cantini, M. , Maddocks, O. D.K. , Salmeron-Sanchez, M. and Machesky, L. (2020) The creatine-phosphagen system is mechanoresponsive in pancreatic adenocarcinoma and fuels invasion and metastasis. Nature Metabolism, 2(1), pp. 62-80. (doi: 10.1038/s42255-019-0159-z) (PMID:32694686)
• Trujillo, S. , Vega, S. L., Song, K. H., San Félix, A., Dalby, M. J. , Burdick, J. A. and Salmeron-Sanchez, M. (2020) Engineered full-length fibronectin-hyaluronic acid hydrogels for stem cell engineering. Advanced Healthcare Materials, 9(21), 2000989. (doi: 10.1002/adhm.202000989) (PMID:33002348)
• Childs, P. G., Reid, S., Salmeron-Sanchez, M. and Dalby, M. J. (2020) Hurdles to uptake of mesenchymal stem cells and their progenitors in therapeutic products. Biochemical Journal, 477(17), pp. 3349-3366. (doi: 10.1042/BCJ20190382) (PMID:32941644) (PMCID:PMC7505558)
• Bjørge, I. M., Salmeron-Sanchez, M. , Correia, C. R. and Mano, J. F. (2020) Cell behavior within nanogrooved sandwich culture system. Small, 16(31), 2001975. (doi: 10.1002/smll.202001975) (PMID:32603002)
• Cantini, M. , Donnelly, H., Dalby, M. J. and Salmeron-Sanchez, M. (2020) The plot thickens: the emerging role of matrix viscosity in cell mechanotransduction. Advanced Healthcare Materials, 9(8), 1901259. (doi: 10.1002/adhm.201901259) (PMID:31815372)
• Huethorst, E., Cutiongco, M. F.A. , Campbell, F. A., Saeed, A. , Love, R., Reynolds, P. M. , Dalby, M. J. and Gadegaard, N. (2020) Customizable, engineered substrates for rapid screening of cellular cues. Biofabrication, 12(2), 025009. (doi: 10.1088/1758-5090/ab5d3f) (PMID:31783378)
• Sarrigiannidis, S. O., Moussa, H., Dobre, O. , Dalby, M. J. , Tamimi, F. and Salmerón-Sánchez, M. (2020) Chiral tartaric acid improves fracture toughness of bioactive brushite-collagen bone cements. ACS Applied Bio Materials, 3(8), pp. 5056-5066. (doi: 10.1021/acsabm.0c00555) (PMID:32904797) (PMCID:PMC7461128)
• Witte, K. , de Andrés, M. C., Wells, J., Dalby, M. J. , Salmeron-Sanchez, M. and Oreffo, R. O.C. (2020) Chondrobags: a high throughput alginate-fibronectin micromass platform for in vitro human cartilage formation. Biofabrication, 12(4), 045034. (doi: 10.1088/1758-5090/abb653)
• Ngandu Mpoyi, E. et al. (2020) Material-driven fibronectin assembly rescues matrix defects due to mutations in collagen IV in fibroblasts. Biomaterials, 252, 120090. (doi: 10.1016/j.biomaterials.2020.120090) (PMID:32413593)
• Orapiriyakul, W. et al. (2020) Nanovibrational stimulation of mesenchymal stem cells induces therapeutic reactive oxygen species and inflammation for 3D bone tissue engineering. ACS Nano, 14(8), pp. 10027-10044. (doi: 10.1021/acsnano.0c03130) (PMID:32658450) (PMCID:PMC7458485)
• Ciccone, G., Dobre, O. , Gibson, G. M. , Rey, J. M., Gonzalez-Garcia, C., Vassalli, M. , Salmeron-Sanchez, M. and Tassieri, M. (2020) What caging force cells feel in 3D hydrogels: a rheological perspective. Advanced Healthcare Materials, 9(17), 2000517. (doi: 10.1002/adhm.202000517) (PMID:32696605)
• Ridone, P., Pandzic, E., Vassalli, M. , Cox, C. D., Macmillan, A., Gottlieb, P. A. and Martinac, B. (2020) Disruption of membrane cholesterol organization impairs the activity of PIEZO1 channel clusters. Journal of General Physiology, 152(8), e201912515. (doi: 10.1085/jgp.201912515) (PMID:32582958)
• Alba, A., Jayawarna, V., Childs, P. G., Dalby, M. J. and Salmeron-Sanchez, M. (2020) Plasma polymerised nanoscale coatings of controlled thickness for efficient solid-phase presentation of growth factors. Materials Science and Engineering C: Materials for Biological Applications, 113, 110966. (doi: 10.1016/j.msec.2020.110966) (PMID:32487385)
• Mattarelli, M., Vassalli, M. and Caponi, S. (2020) Relevant length scales in Brillouin imaging of biomaterials: the interplay between phonons propagation and light focalization. ACS Photonics, 7(9), pp. 2319-2328. (doi: 10.1021/acsphotonics.0c00801)
• Trujillo Munoz, S. , Gonzalez Garcia, C., Rico Tortosa, P., Reid, A., Windmill, J., Dalby, M. J. and Salmeron-Sanchez, M. (2020) Engineered 3D hydrogels with full-length fibronectin that sequester and present growth factors. Biomaterials, 252, 120104. (doi: 10.1016/j.biomaterials.2020.120104)
• Lüchtefeld, I., Bartolozzi, A., Mejía Morales, J., Dobre, O. , Basso, M., Zambelli, T. and Vassalli, M. (2020) Elasticity spectra as a tool to investigate actin cortex mechanics. Journal of Nanobiotechnology, 18, 147. (doi: 10.1186/s12951-020-00706-2)
• Greer, A. et al. (2020) Nanopatterned titanium implants accelerate bone formation in vivo. ACS Applied Materials and Interfaces, 12(30), pp. 33541-33549. (doi: 10.1021/acsami.0c10273) (PMID:32633478) (PMCID:PMC7467557)
• Nosalski, R. et al. (2020) T cell-derived miRNA-214 mediates perivascular fibrosis in hypertension. Circulation Research, 126, pp. 988-1003. (doi: 10.1161/CIRCRESAHA.119.315428) (PMID:32065054) (PMCID:PMC7147427)

2019

• Sun, Z., Feeney, E., Guan, Y., Cook, S. G., Gourdon, D., Bonassar, L. J. and Putnam, D. (2019) Boundary mode lubrication of articular cartilage with a biomimetic diblock copolymer. Proceedings of the National Academy of Sciences of the United States of America, 116(25), pp. 12437-12441. (doi: 10.1073/pnas.1900716116) (PMID:31164421) (PMCID:PMC6589671)
• Cheng, Z. A. et al. (2019) Nanoscale coatings for ultralow dose BMP‐2‐driven regeneration of critical‐sized bone defects. Advanced Science, 6(2), 1800361. (doi: 10.1002/advs.201800361) (PMID:30693176) (PMCID:PMC6343071)
• Rico, P., Rodrigo-Navarro, A. , De la Pena, M., Moulisova, V. , Costell, M. and Salmeron-Sanchez, M. (2019) Simultaneous boron ion-channel/growth factor receptor activation for enhanced vascularization. Advanced Biosystems, 3(1), 1800220. (doi: 10.1002/adbi.201800220)
• Witte, K., Rodrigo-Navarro, A. and Salmeron-Sanchez, M. (2019) Bacteria-laden microgels as autonomous three-dimensional environments for stem cell engineering. Materials Today Bio, 2, 100011. (doi: 10.1016/j.mtbio.2019.100011)
• Bieniek, M., Llopis-Hernandez, V. , Douglas, K., Salmeron-Sanchez, M. and Lorenz, C. D. (2019) Minor chemistry changes alter surface hydration to control fibronectin adsorption and assembly into nanofibrils. Advanced Theory and Simulations, 2019(2), 1900169. (doi: 10.1002/adts.201900169)
• Kareem, M. M., Hodgkinson, T., Salmeron-Sanchez, M. , Dalby, M. J. and Tanner, K. E. (2019) Hybrid core-shell scaffolds for bone tissue engineering. Biomedical Materials, 14(2), 025008. (doi: 10.1088/1748-605X/aafbf1) (PMID:30609417)
• Mas-Moruno, C., Su, B. and Dalby, M. J. (2019) Multifunctional coatings and nanotopographies: towards cell instructive and antibacterial implants. Advanced Healthcare Materials, 8(1), 1801103. (doi: 10.1002/adhm.201801103) (PMID:30468010)
• Aguilera, G., Berry, C. C. , West, R. M., Gonzalez-Monterrubio, E., Angulo-Molina, A., Arias-Carrión, Ó. and Méndez-Rojas, M. Á. (2019) Carboxymethyl cellulose coated magnetic nanoparticles transport across a human lung microvascular endothelial cell model of the blood–brain barrier. Nanoscale Advances, 1(2), pp. 671-685. (doi: 10.1039/c8na00010g)
• Cozens, D., Sutherland, E., Lauder, M., Taylor, G., Berry, C. C. and Davies, R. L. (2019) Pathogenic Mannheimia haemolytica invades differentiated bovine airway epithelial cells. Infection and Immunity, 87(6), e00078-19. (doi: 10.1128/IAI.00078-19) (PMID:30962401) (PMCID:PMC6529648)
• Re, F. et al. (2019) 3D gelatin-chitosan hybrid hydrogels combined with human platelet lysate highly support human mesenchymal stem cell proliferation and osteogenic differentiation. Journal of Tissue Engineering, 10, pp. 1-16. (doi: 10.1177/2041731419845852) (PMID:31105928) (PMCID:PMC6507314)
• Sprott, M. R. , Gallego-Ferrer, G., Dalby, M. J. , Salmeron-Sanchez, M. and Cantini, M. (2019) Functionalisation of PLLA with polymer brushes to trigger the assembly of fibronectin into nanonetworks. Advanced Healthcare Materials, 8(3), 1801469. (doi: 10.1002/adhm.201801469) (PMID:30609243)

2018

• Hay, J. J., Rodrigo-Navarro, A. , Petaroudi, M., Bryksin, A. V., Garcia, A. J., Barker, T. H., Dalby, M. J. and Salmeron-Sanchez, M. (2018) Bacteria-based materials for stem cell engineering. Advanced Materials, 30(43), 1804310. (doi: 10.1002/adma.201804310) (PMID:30209838)
• Dalby, M. J. , García, A. J. and Salmeron-Sanchez, M. (2018) Receptor control in mesenchymal stem cell engineering. Nature Reviews Materials, 3, 17091. (doi: 10.1038/natrevmats.2017.91)
• Cozens, D., Sutherland, E., Marchesi, F. , Taylor, G., Berry, C. C. and Davies, R. L. (2018) Temporal differentiation of bovine airway epithelial cells grown at an air-liquid interface. Scientific Reports, 8, 14893. (doi: 10.1038/s41598-018-33180-w) (PMID:30291311) (PMCID:PMC6173764)
• Bennett, M., Cantini, M. , Reboud, J. , Cooper, J. M. , Roca-Cusachs, P. and Salmeron-Sanchez, M. (2018) Molecular clutch drives cell response to surface viscosity. Proceedings of the National Academy of Sciences of the United States of America, 115(6), pp. 1192-1197. (doi: 10.1073/pnas.1710653115) (PMID:29358406)