A selection of papers from our team

Vibrational stimulation of stem cells

Stimulation of 3D osteogenesis by mesenchymal stem cells using a nanovibrational bioreactor. Penelope M. Tsimbouri, Peter G. Childs, Gabriel D. Pemberton, Jingli Yang, Vineetha Jayawarna, Wich Orapiriyakul, Karl Burgess, Cristina González-García, Gavin Blackburn, Dilip Thomas, Catalina Vallejo-Giraldo, Manus J. P Biggs, Adam S. G. Curtis, Manuel Salmerón-Sánchez, Stuart Reid, and Matthew J. Dalby. Nature Biomedical Engineering 1, 758–770, 2017. doi: 10.1038/s41551-017-0127-4

 

Engineering and understanding of the cell microenvironment

Molecular clutch drives cell response to surface viscosity. Mark Bennett, Marco Cantini, Julien Reboud, Jonathan M. Cooper, Pere Roca-Cusachs, Manuel Salmeron-Sanchez. PNAS February 6, 2018 115 (6) 1192-1197. doi: 10.1073/pnas.1710653115

Receptor control in mesenchymal stem cell engineering. Matthew J. Dalby, Andrés J. García, Manuel Salmeron-Sanchez. Nature Reviews Materials 3, Article number: 17091 (2018). doi:

Nacre Topography Produces Higher Crystallinity in Bone than Chemically Induced Osteogenesis. Enateri V. Alakpa, Karl E. V. Burgess, Peter Chung, Mathis O. Riehle, Nikolaj Gadegaard, Matthew John Dalby, and Maggie Cusack. ACS Nano, 2017, 11 (7), pp 6717–6727. doi: 10.1021/acsnano.7b01044

Engineered microenvironments for synergistic VEGF e Integrin signalling during vascularization. Vladimíra Moulisovaa, Cristina Gonzalez-García, Marco Cantini, Aleixandre Rodrigo-Navarro, Jessica Weaver, Mercedes Costell, Roser Sabater i Serra, Matthew J. Dalby, Andres J. García, Manuel Salmeron-Sanchez. Biomaterials 126 (2017) 61-74. doi: 10.1016/j.biomaterials.2017.02.024

Synergistic growth factor microenvironments. Manuel Salmerón-Sánchez and Matthew J. Dalby. Chemical Communications, 2016,52, 13327. doi: 10.1039/C6CC06888J.

Material-driven fibronectin assembly for high-efficiency presentation of growth factors. Llopis-Hernández V, Cantini M, González-García C, Cheng ZA, Yang J, Tsimbouri PM, García AJ, Dalby MJ, Salmerón-Sánchez M. Science Advances 2016 Aug 26;2(8):e1600188. doi: 10.1126

Protein Adsorption as a Key Mediator in the Nanotopographical Control of Cell Behavior.Ngandu Mpoyi E, Cantini M, Reynolds PM, Gadegaard N, Dalby MJ, Salmerón-Sánchez M. ACS Nano, 2016 Jul 26;10(7):6638-47. doi: 10.1021

Dynamic Surfaces for the Study of Mesenchymal Stem Cell Growth through Adhesion Regulation. Jemma N. Roberts, Jugal Kishore Sahoo, Laura E. McNamara, Karl V. Burgess, Jingli Yang, Enateri V. Alakpa, Hilary J. Anderson, Jake Hay, Lesley-Anne Turner, Stephen J. Yarwood, Mischa Zelzer, Richard O. C. Oreffo, Rein V. Ulijn, and Matthew J. Dalby. ACS Nano, 2016, 10 (7), pp 6667–6679. doi: 10.1021/acsnano.6b01765

Harnessing nanotopography and integrin–matrix interactions to influence stem cell fate. Matthew J. Dalby, Nikolaj Gadegaard and Richard O. C. Oreffo. Nature Materials, 13 558–569, 2014. doi: 10.1038/NMAT3980

Surface mobility regulates skeletal stem cell differentiation. González-García, C., Moratal, D., Oreffo, R.O.C., Dalby, M.J., and Salmerón-Sánchez, M. Integrative Biology, 4 (5). pp. 531-539, 2012. doi:10.1039/c2ib00139j

Role of surface chemistry in protein remodeling at the cell-material interface. Llopis-Hernández, V., Rico, P., Ballester-Beltrán, J., Moratal, D., and Salmerón-Sánchez, M. PLoS ONE, 6 (5). e19610, 2011. doi:10.1371/journal.pone.0019610

Role of material-driven fibronectin fibrillogenesis in cell differentiation. Salmerón-Sánchez, M., Rico, P., Moratal, D., Lee, T.T., Schwarzbauer, J.E., and García, A.J. Biomaterials, 32 (8). pp. 2099-2105, 2011. doi:10.1016/j.biomaterials.2010.11.057

 

Living biointerfaces

Bacteria‐Based Materials for Stem Cell Engineering. Jake J. Hay, Aleixandre Rodrigo‐Navarro, Michaela Petaroudi, Anton V. Bryksin, Andrés J. García, Thomas H. Barker, Matthew J. Dalby, Manuel Salmeron‐Sanchez. Advanced Materials 2018, 30, 1804310, 2018. doi: 10.1002/adma.201804310

Living biointerfaces based on non-pathogenic bacteria support stem cell differentiation.Hay JJ, Rodrigo-Navarro A, Hassi K, Moulisova V, Dalby MJ, Salmeron-Sanchez M. Scientific Reports, 2016 Feb 23;6:21809. doi: 10.1038/srep21809.

Living biointerfaces based on non-pathogenic bacteria to direct cell differentiation. Rodrigo-Navarro, A., Rico, P., Saadeddin, A., Garcia, A. J., and Salmeron-Sanchez, M. Scientific Reports, 4 (5849), 2014. doi:10.1038/srep05849