We are a team of researchers from several schools at the University of Glasgow. Our labs focus on understanding the interactions between materials, proteins and cells to engineer and control cell behaviour and stem cell differentiation.
X-ray preop for surgery of a non-union fracture in a veterinary patient. The patient had already undergone two previous surgeries. Holes from previously used screws are visible. Image by William Marshall
3D printed bone reconstruction and support material. Image by David Shields
Co-culture of human cells and L. lactic bacteria producing recombinant human ECM protein fragments. Image by Aleixandre Rodrigo-Navarro and Jake Hay
Chronic myeloid leukaemia stem cells in interaction with mesenchymal stem cell (MSC) spheroids embedded into collagen type I gel. Image by Caroline Busch and Benjamin Tuck
High aspect ratio surfaces like these on etched Titanium prevent biofilm formation but allow MSCs growth
Mesenchymal stem cell and bacteria encapsulated in alginate gel. Image by Kimia Mohammadi.
Von Kossa staining showing phosphate deposition from human mesenchymal stem cells, a primary step in bone development. Image by Jake Hay and Aleixandre Rodrigo-Navarro
SEM image of Pseudomonas aeruginosa on titanium dioxide nanowires surface. Image by Laila Damiati.
HUVECs reorganizing on the PEA/FN/VEGF surface towards tubular structures of early vessels (or nascent vascular plexus / network); actin is in red, nuclear staining in cyan. Image by Vladimira Moulisova
Endothelial cell-coated beads encapsulated within FN-PEG hydrogels in order to study the pro-angiogenic activity (EC sprouting) of the system when supplementing the media with VEGF. Endothelial cells are activated upon VEGF signals and migrate accordingly in the appropriate environment. Image by Sara Trujillo-Muñoz
Encapsulation of human mesenchymal stem cells in alginate gel droplets using a micro-fluidics set-up. Image by Kimia Mohammadi.
Biofilm of lactococcus lactis. Image by Aleixandre Rodrigo-Navarro and Jake Hay
Chronic myeloid leukaemia stem cells on collagen coated transwell membrane. Image by Caroline Busch and Benjamin Tuck
Sir Bobby Charlton and Eva take a picture with part of the team. Sir Bobby Charlton is the founder of the Find A Better Way charity.
Porcine dorsal root ganglion neuron stained for neurofilament 200 and DAPI nuclear stain
Freeze dried 4PEGMAL hydrogel crosslinked with PEG2SH. Image by Sam Donnelly
SEM image of mesenchymal stem cells on titanium dioxide nanowires. Image by Laila Damiati.
Fibronectin fibrils on a poly(ethyl acrylate) surface. Image by Virginia Llopis-Hernandez
Endothelial cells encapsulated within FN-PEG hydrogels loaded with VEGF. At day 2, ECs reorganise themselves into tubular and interconnected structures. Image by Sara Trujillo-Muñoz
Natural fibronectin fibrils in a cell culture. Image by Cristina Gonzalez-Garcia
X-ray after surgery. Non-union fracture on a veterinary patient. Image by William Marshall
C2C12 myoblast cells on a 3D electrospun poly-lactic acid (PLA) mesh. FN (red), Actin (green) y DAPI (blue). Image by Jose Ballester-Beltran and Maria Almeida