Dr Olivia Johnson-Love introduces the novel method of vibration-based cell engineering in order to alter the fate of stem cells. Cells are highly responsive to mechanical cues in their microenvironment, modulating their behaviour through proliferation, differentiation, or morphological adaptation. This mechanosensitivity has been widely studied for directing stem cell differentiation and offers promising avenues for ...
Dr Udesh Dhawan introduces some of his recent research on how integrins can be utilised in growth factor activation and the development of a mechanobiology-based bone regeneration platform. Integrins are specialised adhesion proteins that enable cells to attach and survive. Take away integrins, and we take away the ability of cells that rely on adhesion ...
In this series of blogs we hear from students recently returned from academic placements about their experiences. Ioanna Rigou is a third-year PhD student under the supervision of Prof Matt Dalby. Hi, I’m Ioanna, a third-year PhD student at the University of Glasgow, and in September 2024, I embarked on an incredible journey with Bio-Tune. ...
In this piece, Dr Matthew Walker summarises the importance of two recently published reviews on the topic of mechanobiology in both cancer and fibrosis, both of which can be accessed here: Walker M, Morton JP. Hydrogel models of pancreatic adenocarcinoma to study cell mechanosensing. Biophysical Reviews. 2024;16(6):851-70. (doi: 10.1007/s12551-024-01265-8) Walker M, Gourdon D, Cantini M. ...
In this series of blogs we hear from students recently returned from academic placements about their experiences. Dora Rogkoti is a fourth-year PhD student under the supervision of Prof Manuel Salmeron-Sanchez. Hello! 😊 I’m Dora, currently a final-year PhD student at the Centre for the Cellular Microenvironment in Glasgow. From September until December 2024, I ...
In this series of blogs we hear from students recently returned from academic placements about their experiences. Euan Urquhart is a fourth-year PhD student under the supervision of Dr Cristina Gonzalez-Garcia. During my placement in Adelaide, I had the incredible opportunity to work with Dr. Christina Bursill’s group in the Vascular Research Centre at the ...