Category: Publications

Harnessing the mechanosensitivity of cells for regenerative therapies and disease detection

Dr Olivia Johnson-Love introduces the novel method of vibration-based cell engineering in order to alter the fate of stem cells. Cells are highly responsive to mechanical cues in their microenvironment, modulating their behaviour through proliferation, differentiation, or morphological adaptation. This mechanosensitivity has been widely studied for directing stem cell differentiation and offers promising avenues for …

Integrin-growth factor dynamics in cancer stemness and tissue regeneration

Dr Udesh Dhawan introduces some of his recent research on how integrins can be utilised in growth factor activation and the development of a mechanobiology-based bone regeneration platform. Integrins are specialised adhesion proteins that enable cells to attach and survive. Take away integrins, and we take away the ability of cells that rely on adhesion …

Hydrogels for the study of cancer and fibrosis

In this piece, Dr Matthew Walker summarises the importance of two recently published reviews on the topic of mechanobiology in both cancer and fibrosis, both of which can be accessed here: Walker M, Morton JP. Hydrogel models of pancreatic adenocarcinoma to study cell mechanosensing. Biophysical Reviews. 2024;16(6):851-70. (doi: 10.1007/s12551-024-01265-8) Walker M, Gourdon D, Cantini M. …

Publication in Materials Today

Dr Kimia Witte has a paper accepted and published in Materials Today Bio journal. The paper looks at bacteria laden microgels as autonomous 3D environments for stem cell engineering and is a result of the research in the lab funded by EPSRC. You can read the full paper here.

Three cool covers

We have started the year with three of our latest papers featured on the covers of journals. The researchers that produced the papers are giddy with happiness to have these incredibly pretty pieces of art to show off. Thanks to the very talented Mark, Sara and Alex! These are the papers: High Efficiency BMP‐2 Coatings: Nanoscale Coatings …

Video abstract for our recent bacteria bio-interfaces paper on Advanced Materials

A video abstract of our recent paper published on the journal Advanced Materials is now available on youtube. “Bacteria‐Based Materials for Stem Cell Engineering” reports our latest progress in our living biointerfaces line of research. Jake, Alex and the rest of the team utilise genetically modified non-pathogenic bacteria to control and direct stem cell biology!

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